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Aerogen White Paper

Aerogen’s vibrating mesh technology, available within the Aerogen® Solo, Aerogen® Pro has been adopted for use across many areas of the hospital during a variety of ventilatory support. Clinical researchers have established its superior performance and a summary of these are below.

Practical strategies for a safe and effective delivery of aerosolized medications to patients with COVID-19 by Ari A

The purpose of this paper is to explain how to deliver aerosolized medications to mild-, sub- intensive, and intensive-care patients with COVID-19 and how to protect staff from exposure to exhaled drop lets during aerosol therapy

Reducing Aerosol-Related Risk of Transmission in the Era of COVID-19: An Interim Guidance Endorsed by the International Society of Aerosols in Medicine

Experts in the field of aerosol have put together a short review to address how aerosol might be safely administered with minimal risk to health care providers. This review was published by the Journal of Aerosols Medicine and Pulmonary Drug Delivery.

Vibrating Mesh Nebulizers in the Emergency Department by Dunne R.B. & Shortt S

This article looks at the Comparison of bronchodilator administraiton with Vibrating Mesh Nebuliser and Standard Jet Nebuliser in the Emergency department.

Pediatric Asthma by Cantu T. & Jenkins L.

This quality improvement plan compared salbutamol delivery with a vibrating mesh aerosol drug delivery device (Aerogen® Solo with Ultra; VM) and a large volume jet nebuliser (JN) in peadiatric patients with asthma or reactive airway disorder who presented to the ED with an acute exacerbation.

Pediatric Asthma by Moody G. et al.

Comparison of Vibrating Mesh Nebulizers & Jet Nebulizers in Pediatric Asthma Patients

References

  1. Dunne RB and Shortt S. Comparison of bronchodilator administration with vibrating-mesh nebulizer and standard jet nebulizer in the emergency department. The American Journal of Emergency Medicine. 2018;36(4):641-646.
  2. Aerogen Internal data on file, Aug 2020
  3. Aerogen Solo System Instruction Manual. Aerogen Ltd.
  4. Ari, A. (2020). Practical strategies for a safe and effective delivery of aerosolized medications to patients with COVID-19. In Respiratory Medicine (Vol. 167). W.B. Saunders Ltd. https://doi.org/10.1016/j.rmed.2020.105987
  5. Dugernier J, Reychler G, Wittebole X, Roeseler J, Depoortere V, Sottiaux T, et al. Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study. Ann Intensive Care [Internet]. 2016/07/23. 2016 Dec [cited 2018 Oct 5];6(1):73. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27447788
  6. MacIntyre NR, Silver RM, Miller CW, Schuler F, Coleman RE. Aerosol delivery in intubated, mechanically ventilated patients. Crit Care Med [Internet]. 1985/02/01. 1985 Feb [cited 2019 Apr 17];13(2):81–4. Available from: http://www.ncbi.nlm.nih.gov/pubmed/39675081
  7. Chweich H et al. Effect on Airflow of Bronchodilator Therapy Delivered via Vibrating-Mesh versus Jet Nebulisers in Acute Asthmatics in an Emergency Department. Poster at ATS. 2019.
  8. Dugernier J et al. SPECT-CT Comparison of Lung Deposition using a System combining a Vibrating-Mesh Nebulizer with a Valved Holding Chamber and a Conventional Jet Nebulizer: a Randomized Cross-over Study. Pharmaceutical Research. 2017;34:290-300.